Ekonomi Manajerial Vincent Gaspersz 36
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Category:Cornell University alumniPractical assessment of breath-hold respiratory gated diffusion-weighted imaging with the echo planar imaging sequence: phantom and in vivo experiments.
To evaluate the potential of the echo planar imaging (EPI) sequence for diffusion-weighted imaging (DWI) of the lungs. The feasibility of a functional DWI study of the lung was studied on a Siemens MAGNETOM 3 Tesla Trio system and a Philips Achieva system. The feasibility of a complete water-fat separation was assessed by means of a two-compartment model. The diffusion sensitivity was determined by measuring the apparent diffusion coefficient (ADC) in a phantom with different b-values. Five healthy subjects were examined on both systems and respiratory gated diffusion-weighted imaging (RESP-DWI) was performed in three of them. First, the blood-pool contrast in a noise suppression experiment and the potential of water-fat separation were studied. Next, measurements in the lung were performed. For all experiments, the mean ADC values were determined. Respiratory gated DWI on a 3 Tesla Trio system led to motion artefacts in three subjects. The technical challenges for water-fat separation and respiratory gating of the diffusion weighting were resolved using the Philips Achieva system. The images from the Philips system were of better quality and no artifact from respiration was observed. The mean ADC values in a phantom were 8.94 × 10(-4) and 3.62 × 10(-4)mm(2)/s for b-values of 0 and 500 s/mm(2), respectively. For three subjects, the mean ADC values for the lung were estimated to 0.32, 0.77, and 0.60 × 10(-4)mm(2)/s with the Trio system and 0.28, 0.48, and 0.30 × 10(-4)mm(2)/s with the Achieva system. Moreover, five patients were examined on a 3T Trio system, using RESP-D
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